Cancer databases
cBioPortal
Cancer genomics exploration
"Interactive cancer-genomics exploration over TCGA, MSK-IMPACT and many more."
About the resource
cBioPortal was developed at Memorial Sloan Kettering Cancer Center and is now maintained by a multi-institution open-source consortium. It provides interactive, web-based exploration of large cancer-genomics datasets — TCGA, MSK-IMPACT, GENIE, MMRF CoMMpass, TARGET pediatric cancer studies, and hundreds of published consortium studies — with views for mutation lollipops, copy-number alterations, gene-expression heatmaps, methylation, pathway enrichment, clinical attributes and Kaplan–Meier survival.
The platform is open-source and can be deployed locally against institution-private cancer-genomics data; the public instance is the standard exploration tool for cancer researchers without programming familiarity. AGPL-3.0.
What you'd use it for
- 01Explore the mutation and CNV profile of a cancer gene across studies
- 02Run a quick survival analysis stratified by alteration status
- 03Compare alteration frequencies between two cancer subtypes
- 04Self-host a private cBioPortal instance over institutional cohorts
How you access it
Public web UIREST APISelf-host (Docker)Local instances at most cancer centres