Genetic & genomic

DisGeNET

Gene–disease associations integrator
"Hundreds of thousands of evidence-scored gene–disease associations."
integrativetext-minedscored

About the resource

DisGeNET integrates gene–disease and variant–disease associations from curated sources (UniProt, ClinVar, Orphanet, CTD, PsyGeNET, the GWAS Catalog and others) and adds large-scale text mining of MEDLINE abstracts, producing a unified, scored dataset of associations.

Each association carries a DisGeNET score reflecting the strength and consistency of supporting evidence across sources. The platform offers a web UI, REST API and a Cytoscape app, and is widely used as a starting point for translational target identification and disease-network analysis.

What you'd use it for

  1. 01Rank candidate genes for a disease by integrated evidence
  2. 02Build a gene–disease network for systems-biology analysis
  3. 03Pull text-mined associations to extend curated knowledge
  4. 04Anchor target-discovery pipelines to a single integrated source

How you access it

Web UIREST APICytoscape appBulk SQL dumps (licence-tiered)

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