Infectious disease & surveillance

NCBI Virus & BV-BRC

Pathogen sequence & bioinformatics
"Open pathogen-sequence archives and integrative bioinformatics."
sequencesviralbacterial

About the resource

NCBI Virus is the curated viral-sequence portal layered over GenBank — taxonomy-aware, with extensive metadata fields, automated host and country detection, and direct integration with NCBI's BLAST and analysis tools. It hosts a fully open alternative to GISAID for SARS-CoV-2 (SRA + GenBank) used by many international labs.

BV-BRC — the Bacterial and Viral Bioinformatics Resource Center — is the NIAID-funded successor to the merged PATRIC, IRD and ViPR programs. It provides genomes, annotations, transcriptomics, proteomics, host-response data, antimicrobial-resistance surveillance and a sizeable analysis service for bacterial and viral pathogens of human importance.

What you'd use it for

  1. 01Pull viral sequences for a pathogen via fully open NCBI Virus
  2. 02Run AMR and pangenome analysis in BV-BRC workspaces
  3. 03Cross-reference host-response transcriptomics with pathogen genomics
  4. 04Use as an open mirror complement to GISAID for SARS-CoV-2

How you access it

Web UIFTP downloadsBV-BRC analysis service workspacesBLAST

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